The crash happened about 3 p.m. and closed Grubb Road for 2½ hours.
A 2010 Ford SUV driven by Jennifer R. Ramsey, 38, of Bear, was westbound on Andy’s Lane approaching Grubb Road and failed to see two motorcycles as she entered the intersection, police said.
Her SUV was struck by a Suzuki motorcycle, driven by Dylan Desmond, 19, of Wilmington, and a 1998 Honda RF3 motorcycle, driven by Joshua Cortes, 19, of Claymont.
Police said both bikes were traveling at high speed.
When Desmond’s bike struck the front left side of the Ford, he was ejected and landed in a ditch. The impact ruptured his fuel tank and his motorcycle became engulfed in flames.
Cortes’ bike slid about 115 feet before hitting the left rear door of the SUV.
Desmond was treated at the scene by New Castle County paramedics, then taken by ambulance to Christiana Hospital with serious but not life-threatening injuries, police said.
Cortes was injured but declined treatment at the scene.
Ramsey and her 4-year-old son, who was a passenger in the SUV, were taken to Christiana and treated for injuries, police said.
Troopers cited her for failure to remain stopped at a stop sign.
Police are still investigating and said charges are pending against Cortes and Desmond.